AI0024 Glucagon
Molecular Formula: C153H225N43O49S
Relative Molecular Mass: 3482.80 g/mol
CAS-Number: 16941-32-5
Long-term Storage: -20 ± 5°C
Sequence: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH
Fields of Application: Hypoglycemia (diabetes mellitus) Active Substance: Glucagon is produced in the α-cells of the islets of Langerhans. The hormone opposes the action of insulin. Glucagon promotes the synthesis and mobilization of glucose from glycogen in the liver. The generation of glucose from lipids is regulated by glucagon as well. Additionally, glucacon induces inotropic and chronotropic effects by raising the concentration of cAMP.
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